KP Phyto’s Newsletter
11 Oct 2024
NEWSLETTER
SHARING KNOWLEDGE & HELPING CUSTOMERS EXCEL
Vol 12/2024| Editor: Kerry Hughes, MSc.
Driving the global
supply chain in
Botanical Ingredients.
KP Phyto is positioned to
take on global supply chain
demands, and is the Indian
market leader catered to a
wide range of ingredients for
food, pharma, nutraceutical,
dietary supplements and
cosmetics.Thank you for your
interest in our newsletter &
allowing us to provide you
with deep dive perspectives
on Indian botanicals.
Newsletter Vol 12/2024
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Adaptogenic Amrita
Native to the Indian subcontinent, Guduchi (Tinospora
cordifolia) is a large deciduous climbing shrub with heart-
shaped leaves and a succulent stem. It produces small,
yellowish flowers and drupes that turn red when mature. It
commonly climbs on other trees, including Mango and
Neem trees.
The stems of Guduchi are sometimes used in textile
dyeing for their yellow tint, while the roots and leaves are
utilized in traditional crafts and rituals. Although it is not
commonly used in culinary applications, its bitter-tasting
stem extracts are occasionally incorporated into health
tonics and supplements.
Various parts of the plant are used in different applications
the stems are primarily harvested for medicinal purposes,
while the leaves can be used in compost and organic
fertilizers to enhance soil quality. Guduchi’s woody parts
KP Phyto’s Newsletter
11 Oct 2024
to enhance soil quality.Guduchi’s woody parts have some
traditional utility as small implements or for burning in
ceremonial fires.
In Ayurveda
In Ayurveda, Guduchi is revered as a Rasayana herb,
believed to promote longevity and rejuvenation, enhance
memory, digestion, immunity, and improve overall vitality. It
is referred to as ‘Amrita’, referring to it as the nectar of the
gods and for its use promoting immortality.
Considered a Tri-Doshic herb, it is commonly used to
support liver, gastrointestinal, skin and genitourinary health,
and is often used as a balancing herb in many Ayurvedic
formulations.
Constitutents
The whole plant is used in traditional medicinal
preparations. The bioactive constituents identified in
Guduchi include tinosporin, columibin, chasmanthin and
palmarin (whole plant); the alkaloids, tinosporide, tinosporic
acid, tinosporol and protoberberine (leaves); berberine,
palmitine, magniflorin, tembertarine (stems); as well as
lignans, diterpenes, furan lactones, arabinogalactan, cordifol
and cordifolide.
The Science
Through scientific investigation, Guduchi has been found to
exhibit a wide-range of activities, including promoting
immune, bone, cognitive, kidney, respiratory, metabolic and
liver health, radioprotection, cytokine balance, comfort,
antioxidant, cognitive and blood sugar balance.
Various constituents and bitter principles are present in
Guduchi that have insulin mimicking and releasing effects,
Newsletter Vol 12/2024
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KP Phyto has invested heavily in
understanding the points along
the supply chain that must be
controlled for the best quality
outcomes in Tinospora
cordifolia ingredient quality. We
also invest into the
understanding and
development of the research
behind Indian traditional
botanicals…with a focus this
month on Tinospora cordifolia!
KP Phyto’s Newsletter
11 Oct 2024
and positive benefits have been found for blood sugar
balance clinically. In preclinical and clinical studies it has
been found to be capable of reducing fasting blood sugar,
lipid levels and glycated hemoglobin. Several mechanisms
that have been postulated are that it may effect blood sugar
balance by increasing pancreatic excretion of insulin,
increasing the tissue utilization of glucose or by decreasing
the absorption from the gastrointestinal tract.
The Evolving Science
Guduchi is a good example of the phytochemical complexity
of herbs, as it has many known bioactives that come from
distinct and non-overlapping chemical classes, and the
traditional use of the whole plant.Moreover, the wide range
of activities that have been confirmed scientifically set the
stage for an herb that is capable of affecting multiple tissues
throughout the body all at the same time—in other words,
having a more balancing or modulating effect.
One strong area of traditional use, in Ayurveda Guduchi has
often been used for its immunomodulating role and for
promoting a balanced immune response. Guduchi’s
immunomodulating effects serve as a good example of how
our understanding of this herb represents the complexity
and balance through which herbs may possibly be
benefitting health.
Specifically, through scientific investigation, Guduchi has
been confirmed to modulate key signalling pathways having
to do with cell proliferation, cytokine balance and
immunomodulation. As its immunomodulatory activity has
been shown to be mediated through a variety of
phytochemicals from diverse chemical classes, including
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KP Phyto’s Newsletter
11 Oct 2024
polysaccharides, alkaloids, cadinane sesquiterpenes, and
phenylpropanoid glycosides, the diverse signalling networks
it elicits is thought to bring about a more balanced immune
response.
I find it interesting that the science is uncovering the multi-
pronged mechanism of this herb, pointing to its ability to
produce a balanced benefit in to our physiology, and all
along Ayurveda has considered this herb as “tri-doshic”. It’s
tri-doshic nature means that Ayurveda has considered it to
be able to have a more balanced effect throughout the
various body constitutions.
It is exciting to watch the science on botanicals evolve
through the years and lead us to a place of understanding
about botanicals that is completely different than that of the
‘Pharma’ approach. In other words, if were to take a step
back and view herbs, like Guduchi, with their multiple
bioactive compounds and muti-pronged effects on multiple
tissues in the body, we have a new lens to understand that
herbs stand apart from drugs and the Pharma approach, and
that they should be treated as the beautiful and complex
solutions that nature has given us to the complexity of life.
Newsletter Vol 11/2024
For more information ....
on Tinospora cordifolia &
other ingredients.
Visit:
https://phytoextractskp.com/
tinofolia/
or mail us at.
E:Info@phytoextractskp.com
4
Meet us at Supply
Side West 2024
We are delighted to invite you
to visit our booth 2345, at
Supply Side West , from
October 30-31st ,
2024.Discover the ultimate
source of authentic botanical
extracts and experience
firsthand quality and innovation
that set us apart in the
industry.
KP Phyto’s Newsletter
11 Oct 2024
© K Patel Phyto
Extractions Pvt Ltd(India)
Notice:-
This content is for
informational and educational
purposes only. It is not
intended to provide medical
advice or to take the place of
such advice or treatment from
a personal physician.
Kerry Hughes, MSc., The Ethnobotanical Explorer,
Kerry Hughes, MSc.,The Ethnobotanical Explorer & principal
for EthnoPharm, is an Ethnobotanist and Registered
Herbalist, with a 20-year record of success in natural product
development. EthnoPharm specializes in innovative product
formulation, education, and nexus-of-market opportunity
identification.
Newsletter Vol 12/2024
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