A high-performance extract of Andrographis paniculata crafted by KP-Phyto
The herb is revered in Ayurveda as a true mark of botanical integrity and has been relied upon for centuries to manage inflammatory disorders, respiratory imbalances, and to restore overall immunity. Because, in Ayurveda, bitterness is clarity. It clears, cleanses, and corrects! Standardizing these bitter origins and ancient roots, KP Phyto thus came up with Andropan™, a quiet tribute to Kalmegh’s legacy. With a taste that tests the tongue and results that withstand scrutiny, Andropan™ takes the undiluted strength of Kalmegh to the next generation of wellness solutions.
The Bitter Revolution: Kalmegh Reimagined
Once confined to bitter decoctions and village medicine chests, Andrographis paniculata or Kalmegh has now emerged as one of the most promising botanicals in the world of integrative medicine. And its rise is no coincidence.
The remarkable pharmacology of andrographolides, including immunomodulatory, anti-inflammatory, antiviral, hepatoprotective, and antioxidant actions, has been highly mapped by contemporary research today. The andrographolides act by balancing Th1/Th2 immune responses, preventing oxidative damage to hepatic tissues, and inhibiting pro-inflammatory mediators such as TNF-α and IL-6. From viral fevers and respiratory tract infections to inflammatory bowel disease and post-viral fatigue syndromes, these actions have been proven to be effective in a variety of clinical contexts.
Yet for all its promise, Kalmegh’s clinical utility has long been hindered by a recurring obstacle: consistency. Variations in sourcing, extraction, and processing often lead to erratic levels of active compounds. KP Phyto’s Andropan™ changes that narrative.
What Makes Andropan™ Unique?
Andropan™ represents the next generation of Kalmegh extracts, scientifically validated, pharmaceutically compliant, and tailored for modern product development. Standardized to a USP-grade Andrographolide content, Andropan™ delivers consistent potency with ethanol-based extraction and full-spectrum traceability from farm to finished formulation.
Clinical Validation: When Tradition Meets Data
Can a bitter herb really stand up to modern clinical scrutiny? With Andropan™, the answer is a resounding yes.
To validate its efficacy, a randomized, double-blind, placebo-controlled clinical trial was conducted on 38 adults (aged 18–65) suffering from mild to moderate upper respiratory tract infections (URTIs). These were everyday cases of sore throat, cough, nasal congestion, or low-grade fever symptoms familiar to millions. But the intervention wasn’t ordinary.
Participants received low dose of 150 mg of Andropan™ twice daily for 7 days, while the placebo group received an inert equivalent. And then came the results.
By Day 7, the Andropan™ group reported a 4.8-fold greater reduction in cough severity compared to the placebo (p < 0.01). Two out of three patients in the Andropan™ arm experienced complete symptom relief, while just one in three in the placebo group could say the same. Improvements in sore throat, nasal congestion, and overall energy were also significantly higher in the treatment group.
What stood out even more was the safety. No red flags. No adverse changes in liver or kidney markers. The extract was well-tolerated, with only a handful of patients reporting mild gastric unease, nothing that required medical intervention.
This isn’t raw herb powder but rather, it’s a soluble, bioavailable, excipient-free extract designed for versatility across syrups, tablets, capsules, and suspension-based systems. With its high aqueous solubility, clean-label credentials, and proven immune-modulating and anti-inflammatory benefits, Andropan™ offers formulators more than just an active ingredient. It offers a reliable, globally accepted botanical that performs both in the lab and in the marketplace.
Ayurvedic Logic That Meets Modern Application.
Kalmegh (Andrographis paniculata) is classically described as possessing:
- Rasa (Taste):
Tikta (Intensely bitter)
- Guna (Qualities):
Laghu (light), Ruksha (dry)
- Virya (Potency):
Shita (cooling)
- Vipaka (Post-digestive effect):
Katu (pungent)
- Prabhava (Unique effect):
- Jwara-hara (fever-relieving)
- Ojovardhaka (immune modulatory)
- Swasa-kasahara (relieves cough and breathing difficulty)
What does it mean?
Kalmegh (Andrographis paniculata) is a classic example of a Tikta rasa pradhana Dravya in Ayurveda, meaning that its bitter taste serves as a therapeutic directive in addition to being a sensory note. The distinctive cleansing, drying, and detoxifying qualities of Kalamegh are all attributed to its Tikta rasa (bitter taste) in conjunction with the Laghu (light) and Ruksha (dry) gunas.
Kalmegh has two other functions:
- It has cooling power (Shita virya) and
- A pungent post-digestive transformation (Katu vipaka).
Due to both which, it also reduces inflammatory heat (Pitta) and improves digestive transformation without taxing the body’s water element, Kapha. The same also underpins its classical Doshakarma as a Kapha-Pitta pacifier, especially valuable in managing conditions like Jwara (fever), Kasa–Shwasa (respiratory issues), and immune responses.
Andropan™ allows formulators to draw from this rich Ayurvedic context without having to oversimplify or dilute it. You don’t need to sell a traditional concoction; you can build a scientifically credible product that works with real outcomes while still holding a deep cultural and botanical resonance.
The KP-Phyto Commitment: Purity, Precision, and Purpose
Every batch of Andropan™ reflects:
- Solvent-Free Green Processing
Without introducing solvents or bringing heat damage, we use eco-friendly extraction technologies that preserve the natural chemistry of Kalmegh. This helps in the maximum retention of the active constituents like andrographolides while keeping the process clean, safe, and sustainable.
- Phytochemical Fingerprint Matching
Using advanced analytical tools (like HPLC and LC-MS), we match the full phytochemical profile of Kalmegh as found in nature. This ensures that Andropan™ isn’t just standardized for a single active ingredient, rather it mirrors the synergistic complexity of the plant in a more bioavailable form.
- Global Compliance & Clinical Relevance
Each batch of Andropan™ is rigorously tested to meet international safety standards:
- Microbial safety (no contamination)
- Residual solvent-free (clean processing)
- Consistent active levels (clinically useful doses of andrographolides)
Whether for EU, US, or APAC markets, Andropan™ meets all regulatory benchmarks.
- Transparent Sourcing & Quality Control
From seed to finished extract, every step of Andropan™’s journey is fully traceable. We partner with trusted cultivators, maintain non-GMO, pesticide-free sourcing, and follow multi-stage quality control protocols.
Not Just an Extract. A Strategy.
Andropan™ is not a bulk powder disguised as science. It is designed to match the phytochemical complexity of the whole herb, in a concentrated, stable, and soluble form. Every batch is standardized to deliver consistent andrographolide levels, so formulators can rely on predictability and performance, and not guesswork.
Through Andropan™, it is proven that the bitter profile is not a flaw, but authenticity. You don’t hide it; you build around it. Andropan™ lets your formulation tell a story of clinical action and Ayurvedic depth, with no masks or gimmicks. Whether you’re crafting a tonic, syrup, effervescent powder, or capsule blend, Andropan™ offers more than botanical value. It offers formulation integrity, Ayurvedic soul, and clinical substance.
This isn’t marketing fluff. This is herbalism evolved.
